diff --git a/Lib/fontTools/__init__.py b/Lib/fontTools/__init__.py
index 3d4db6223..82da9b70b 100644
--- a/Lib/fontTools/__init__.py
+++ b/Lib/fontTools/__init__.py
@@ -3,6 +3,6 @@ from fontTools.misc.loggingTools import configLogger
 
 log = logging.getLogger(__name__)
 
-version = __version__ = "4.21.2.dev0"
+version = __version__ = "4.22.0"
 
 __all__ = ["version", "log", "configLogger"]
diff --git a/NEWS.rst b/NEWS.rst
index ab1a6115d..b07f5b181 100644
--- a/NEWS.rst
+++ b/NEWS.rst
@@ -1,3 +1,6 @@
+4.22.0 (released 2021-04-01)
+----------------------------
+
 - [ttLib] Remove .Format from Coverage, ClassDef, SingleSubst, LigatureSubst,
   AlternateSubst, MultipleSubst (#2238).
   ATTENTION: This will change your TTX dumps!
diff --git a/setup.cfg b/setup.cfg
index 358fa8421..230175c6f 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -1,5 +1,5 @@
 [bumpversion]
-current_version = 4.21.2.dev0
+current_version = 4.22.0
 commit = True
 tag = False
 tag_name = {new_version}
diff --git a/setup.py b/setup.py
index fbf6117a5..d1c5a4f67 100755
--- a/setup.py
+++ b/setup.py
@@ -441,7 +441,7 @@ if ext_modules:
 
 setup_params = dict(
 	name="fonttools",
-	version="4.21.2.dev0",
+	version="4.22.0",
 	description="Tools to manipulate font files",
 	author="Just van Rossum",
 	author_email="just@letterror.com",